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RNA golden tests, pipeline guide, changelog, contributing guide - #26

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Oct 21, 2026
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  • Golden-output tests for the spliced presets (rna_*, cdna_* in expected.tsv) on a new deterministic synthetic dataset: genes on both strands with isoforms, micro-exons, a non-canonical intron and a processed pseudogene; direct-RNA-like reads (poly(A), half with U) and cDNA-like reads (adapters, both orientations). Hashes identical on AVX2, SSE and scalar paths. DNA hashes unchanged.
  • docs/pipelines.md — replacing minimap2 commands, ONT's wf-human-variation on bonefish BAMs, downstream tools, containers.
  • CHANGELOG.md, CONTRIBUTING.md (build/test, output-change policy and validation expectations), issue templates (bug report asks for version, command, CPU, data).
  • README links to the new pages.

🤖 Generated with Claude Code

…g, contributing guide, issue templates

- regression: rna_* / cdna_* cases (-x rna, -x cdna, splice:hq, splice alias, --cs, --MD
  --eqx, --junc-bed) on a new synthetic spliced dataset (scripts/make_regression_rna_data.py:
  24 genes on both strands, isoforms, micro-exons, a non-canonical intron, a processed
  pseudogene; direct-RNA-like reads with poly(A) and U, cDNA-like reads with adapters). Same
  hashes on the AVX2, SSE and scalar paths.
- docs/pipelines.md: replacing minimap2 commands, ONT's wf-human-variation with bonefish BAMs,
  downstream tools, containers.
- CHANGELOG.md, CONTRIBUTING.md (build, tests, output-change policy), issue templates.

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>
@DylanCosto
DylanCosto merged commit d7414b4 into main Oct 21, 2026
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@DylanCosto
DylanCosto deleted the repo-complete branch October 21, 2026 21:35
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